Study of Clinico-histopathological Correlation of Papulosquamous Disorders at Tertiary Care Hospital

The aims of the study weres to determine the clinical & histopathological correlation of papulosquamous disorders and to know various tissue reaction patterns of papulosquamous disorders. A total 179 patients with clinical features of papulosquamous disorders were included in this study. Biopsy was taken and sent for haematoxylin and eosin stain and examination. Finally clinico-histopathological correlation was done & noted. Out of the 179 patients of papulosquamous skin lesions, in 123 (68.72%) patients the histopathological findings confirmed the clinical diagnosis while in 56 (31.28%) patients the histopathological findings were differed from clinical judgment. Degree of positive correlation was maximum in lichen planus (92.9%) & pityriasis lichenoides chronic (80%) while it was least in psoriasiform eczema (32%). Interestingly we have found two tissue reaction patterns lichenoid and psoriasiform in papulosquamous skin lesions. Our study was designed to explore hypothesis that certain tissue reaction patterns, lichenoid and psoriasiform, might be common in papulosquamous skin disorders which lead to new approaches for better understanding of etiopathogenesis and management of same group of disorders. The papulosquamous disorders are complex to diagnose & are difficult to identify and manage. Certain tissue reaction patterns like lichenoid and psoriasiform are common in papulosquamous skin disorders which lead to new approaches for better understanding of etiopathogenesis and management of same group of disorders.